Alt-R not working

It seems my Alt-r combination is not working on any of my apps on my Dell Desktop. I tried on Reaper (my DAW) and it didn’t work.
I then tried Sonic Pi 3.1 on my laptop and the alt-r works fine.
So it really isn’t a Sonic Pi problem.
I used a key event viewer to analyse my keystrokes and the when alt-r is pressed I am not registering the ‘down’ stroke of the ‘r’ key.
It’s not sonic pi, it’s not my keyboard (i tested it on my laptop) so it must be something in my desktop setup that is causing it. It’s frustrating, but not a sonic pi problem so I won’t take up any more of your time - unless you have any ideas? Thanks anyway.